22Q Deletion Syndrome is genetic condition caused by a deletion in the 22nd Chromosome. It is also know has Velo-Cardio-Facial Syndrome (VCFS) and DiGeorge Syndrome. The most common features of this syndrome are:
- palatal abnormalities (such as cleft lip and/or palate)
- feeding difficulties
- conotruncal heart defects (e.g., tetralogy of Fallot, interrupted aortic arch, ventricular septal defects, vascular rings)
- hypocalcemia (low blood calcium levels)
- mental retardation (usually borderline to mild)
- IQs are generally in the 70 to 90 range
- psychiatric disorders in adults (e.g., schizophrenia, bipolar disorder)
- severe immunologic dysfunction (an immune system which does not work properly due to abnormal T-cells, causing frequent infections).
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